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Sildenafil Nanosuspension by QbD: Unlocking New Possibilities in Pharmaceutical Compounding

Article ID 014001 | Md. Rezowanur Rahman, Mohammad Faisal Hossain, Sartaz Araf, A.B.M. Asikur Rahman

Introduction Recent advancements in drug delivery systems have revolutionized medication efficacy and availability, offering innovative solutions for addressing various therapeutic challenges.1 Among these advancements, nanosuspensions have emerged as a cutting-edge technology with significant advantages.2 These colloidal dispersions are complex mixtures ... Read More

Penicillin Allergy De-labeling: A Missed Opportunity for Antimicrobial Stewardship

Article ID 013001 | Shobhit Sood, Emily Lester

Introduction Beta-lactams are a broad class of antibiotics that include penicillins, cephalosporins, carbapenems, and monobactams. Their versatility, substantial efficacy, safety, and cost-effectiveness make beta-lactams the most frequently prescribed antibiotic class, and as a result, the class for which hypersensitivity reactions ... Read More

IPF Pipeline: What is the Current and Future Status on Idiopathic Pulmonary Fibrosis Drug Development?

Article ID 012001 | Dalton Oliver, Mohammad Faisal Hossain

Introduction Fibrosis is the overgrowth, stiffening, and/or scarring of tissues that leads to an excess deposition of extracellular matrix (ECM) components. Pulmonary fibrosis (PF) is a chronic progressive lung disease of multiple triggers, in which progression of declining lung function ... Read More

The Significance of Patient Counseling on Treatment Outcome of Patients with Superficial Fungal Infections in a Tertiary Level Hospital in Bangladesh

Article ID 011008 | Fatema Akhter, Mohammad Faisal Hossain, Md. Mazharul Islam Chowdhury, Abdulla Mamun

Introduction Superficial fungal infections (SFIs) are very common skin infections that affect individuals. SFIs impose a significant burden, with a prevalence of approximately 20-25% among dermatology patients [1]. SFIs can be caused by various types of fungi, including dermatophytes, yeasts, ... Read More

A Comparative Review: Examining the Health Benefits of Dietary Supplement Coenzyme Q10 in Hypertension, Dyslipidemia, and Statin Associated Myopathy

Article ID 011007 | Shivkumar Vijayakumar, Mohammad Faisal Hossain

Introduction Hypertension, affecting over 30% of the adult population worldwide, constitutes a major factor contributing to other deadly diseases such as chronic kidney disease, stroke, and heart failure leading to death. Regrettably, only about 1 in 5 adults with hypertension ... Read More

Understanding Water Activity: A Key Component in Determining Beyond Use Date (BUD) in Pharmaceutical Compounding

Article ID 011006 | Mohammad Faisal Hossain

Introduction Water, which is utilized as a significant component for a multitude of purposes in the pharmaceutical industry, plays a crucial role in the processing, formulating, and manufacturing of pharmaceutical products, active ingredients, intermediates, and analytical reagents. In addition, water ... Read More

Quality Assurance in Pharmaceutical Compounding (QA Part 1): Verification of Certificate of Analysis (CoA)

Article ID 011005 | Mohammad Faisal Hossain

Introduction The quality, safety, and effectiveness of compounded preparations rely on the correct selection of ingredients. QA is a system that guarantees consistent adherence to quality standards within the compounding process.1,2 The USP monograph outlines the expectations for a medicine's ... Read More

Steps to be taken to correctly compound slow-release capsules: A Simplified Compounding Approach

Article ID 011004 | Md. Mazharul Islam Chowdhury, Kenna Fields, Machaela Keene, Randy Mullins, Mohammad Faisal Hossain

Introduction The extended-release (ER) dosage forms are a notable addition to the pharmacy field for drugs with a very short half-life compared to conventional solid dosage forms. Terms such as “prolonged release,” “delayed release,” “long-acting,” and “sustained release” have been ... Read More

Compounding Lidocaine Topical Gel: An Exhibit of a “Master Formulation and Compounding Records” for 503A pharmacies

Article ID 011003 | Mohammad Faisal Hossain

Introduction Lidocaine is frequently used as a local anesthetic drug. It is a weak base with a pKa of 7.9 and falls under the BCS class II drug (high permeability and low solubility) category.1 The molecular weight is 234.34 g/mol. ... Read More

Engaging the New Generation: A Study on Student Pharmacists’ Views on the Effectiveness of Pre-Laboratory Video Tutorials in Pharmaceutical Compounding

Article ID 011002 | Bishen Kafley, Mohammad Faisal Hossain

Introduction Over the last two decades, compounding errors have led to severe consequences and fatalities in the United States.1 These incidents are attributed to human error,  lack of knowledge,  poor skills,  and retention in following proper procedures of the pharmaceutical ... Read More

Prospects and Challenges of Using an Autocompounder in a 503A Pharmacy for Non-Sterile Compounding: A Comparative Study

Article ID 011001 | Mohammad Faisal Hossain, Makayla Funk, Aaron Ratliff, Dalton Oliver

Introduction Pharmaceutical compounding, as defined by the U.S. FDA, is generally “a practice in which a licensed pharmacist, a licensed physician, or, in the case of an outsourcing facility, a person under the supervision of a licensed pharmacist, combines, mixes, ... Read More
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